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Area under the Curve-Based Dosing of Vancomycin in Critically Ill Patients Using 6-Hour Urine Creatinine Clearance Measurement

BACKGROUND: The area under the curve- (AUC-) guided vancomycin dosing is the best strategy for individualized therapy in critical illnesses. Since AUC can be calculated directly using drug clearance (CL(van)), any parameter estimating CL(van) will be able to achieve the goal of 24-hour AUC (AUC(24 h...

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Publicat a:Crit Care Res Pract
Autors principals: Shahrami, Bita, Najmeddin, Farhad, Ghaffari, Saeideh, Najafi, Atabak, Rouini, Mohammad Reza, Mojtahedzadeh, Mojtaba
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775160/
https://ncbi.nlm.nih.gov/pubmed/33425384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8831138
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