Whole-genome sequence analysis and comparisons between drug-resistance mutations and minimum inhibitory concentrations of Mycobacterium tuberculosis isolates causing M/XDR-TB

Drug resistance (DR) remains a major challenge for tuberculosis (TB) control. Whole-genome sequencing (WGS) provides the highest genetic resolution for genotypic drug-susceptibility tests (DST). We compared DST profiles of 60 Mycobacterium tuberculosis isolates which were drug resistant according to...

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Bibliographic Details
Published in:PLoS One
Main Authors: Nonghanphithak, Ditthawat, Kaewprasert, Orawee, Chaiyachat, Pratchakan, Reechaipichitkul, Wipa, Chaiprasert, Angkana, Faksri, Kiatichai
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775048/
https://ncbi.nlm.nih.gov/pubmed/33382836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244829
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