The Crystal Structures of Bacillithiol Disulfide Reductase Bdr (YpdA) Provide Structural and Functional Insight into a New Type of FAD-Containing NADPH-Dependent Oxidoreductase

[Image: see text] Low G+C Gram-positive Firmicutes, such as the clinically important pathogens Staphylococcus aureus and Bacillus cereus, use the low-molecular weight thiol bacillithiol (BSH) as a defense mechanism to buffer the intracellular redox environment and counteract oxidative stress encount...

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Veröffentlicht in:Biochemistry
Hauptverfasser: Hammerstad, Marta, Gudim, Ingvild, Hersleth, Hans-Petter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2020
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774306/
https://ncbi.nlm.nih.gov/pubmed/33326741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00745
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