Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway

Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease worldwide. Hydrogen sulfide (H(2)S) is involved in a wide range of physiological and pathological processes. Nevertheless, the mechanism of action of H(2)S in NAFLD development has not been fully clarified. Here, the reduced...

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Vydáno v:Front Pharmacol
Hlavní autoři: Wu, Dongdong, Zhong, Peiyu, Wang, Yizhen, Zhang, Qianqian, Li, Jianmei, Liu, Zhengguo, Ji, Ailing, Li, Yanzhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774297/
https://ncbi.nlm.nih.gov/pubmed/33390956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.585860
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