The Bactericidal Fatty Acid Mimetic 2CCA-1 Selectively Targets Pneumococcal Extracellular Polyunsaturated Fatty Acid Metabolism

Streptococcus pneumoniae, a major cause of pneumonia, sepsis, and meningitis worldwide, has the nasopharynges of small children as its main ecological niche. Depletion of pneumococci from this niche would reduce the disease burden and could be achieved using small molecules with narrow-spectrum anti...

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Vydáno v:mBio
Hlavní autoři: Reithuber, Elisabeth, Nannapaneni, Priyanka, Rzhepishevska, Olena, Lindgren, Anders E. G., Ilchenko, Oleksandr, Normark, Staffan, Almqvist, Fredrik, Henriques-Normark, Birgitta, Mellroth, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773995/
https://ncbi.nlm.nih.gov/pubmed/33323510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03027-20
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