Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue

The clinical presentation of dengue virus (DENV) infection is variable. Severe complications mainly result from exacerbated immune responses. Type I interferons (IFN-I) are important in antiviral responses and form a crucial link between innate and adaptive immunity. Their contribution to host defen...

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Vydáno v:Front Immunol
Hlavní autoři: Upasani, Vinit, Scagnolari, Carolina, Frasca, Federica, Smith, Nikaïa, Bondet, Vincent, Vanderlinden, Axelle, Lay, Sokchea, Auerswald, Heidi, Heng, Sothy, Laurent, Denis, Ly, Sowath, Duong, Veasna, Antonelli, Guido, Dussart, Philippe, Duffy, Darragh, Cantaert, Tineke
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773824/
https://ncbi.nlm.nih.gov/pubmed/33391269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.605087
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