Tobacco smoking induces metabolic reprogramming of renal cell carcinoma

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is the most common histologically defined renal cancer. However, it is not a uniform disease and includes several genetic subtypes with different prognoses. ccRCC is also characterized by distinctive metabolic reprogramming. Tobacco smoking (TS) is...

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Udgivet i:J Clin Invest
Main Authors: Reigle, James, Secic, Dina, Biesiada, Jacek, Wetzel, Collin, Shamsaei, Behrouz, Chu, Johnson, Zang, Yuanwei, Zhang, Xiang, Talbot, Nicholas J., Bischoff, Megan E., Zhang, Yongzhen, Thakar, Charuhas V., Gaitonde, Krishnanath, Sidana, Abhinav, Bui, Hai, Cunningham, John T., Zhang, Qing, Schmidt, Laura S., Linehan, W. Marston, Medvedovic, Mario, Plas, David R., Figueroa, Julio A. Landero, Meller, Jarek, Czyzyk-Krzeska, Maria F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2021
Fag:
Clinical Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773408/
https://ncbi.nlm.nih.gov/pubmed/32970633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140522
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