Galectin-7 downregulation in lesional keratinocytes contributes to enhanced IL-17A signaling and skin pathology in psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by inflammatory cell infiltration, as well as hyperproliferation of keratinocytes in skin lesions, and is considered a metabolic syndrome. We found that the expression of galectin-7 is reduced in skin lesions of patients with psoriasis....

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Vydáno v:J Clin Invest
Hlavní autoři: Chen, Hung-Lin, Lo, Chia-Hui, Huang, Chi-Chun, Lu, Meng-Ping, Hu, Po-Yuan, Chen, Chang-Shan, Chueh, Di-Yen, Chen, Peilin, Lin, Teng-Nan, Lo, Yuan-Hsin, Hsiao, Yu-Ping, Hsu, Daniel K., Liu, Fu-Tong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773376/
https://ncbi.nlm.nih.gov/pubmed/33055419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130740
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