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Targeting the mutant p53 secretome

While p53 is the most highly mutated and perhaps best studied tumor suppressor protein related to cancer, it remains refractory to targeted therapeutic strategies. In this issue of the JCI, Tan and colleagues investigated the mechanistic basis of the mutant p53 secretome in preclinical models of lun...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Sehgal, Kartik, Barbie, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773369/
https://ncbi.nlm.nih.gov/pubmed/33393496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143945
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