Hi-C implementation of genome structure for in silico models of radiation-induced DNA damage

Developments in the genome organisation field has resulted in the recent methodology to infer spatial conformations of the genome directly from experimentally measured genome contacts (Hi-C data). This provides a detailed description of both intra- and inter-chromosomal arrangements. Chromosomal int...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Ingram, Samuel P., Henthorn, Nicholas T., Warmenhoven, John W., Kirkby, Norman F., Mackay, Ranald I., Kirkby, Karen J., Merchant, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773326/
https://ncbi.nlm.nih.gov/pubmed/33326415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008476
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