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Proximity-dependent proteomics reveals extensive interactions of Protocadherin-19 with regulators of Rho GTPases and the microtubule cytoskeleton

Protocadherin-19 belongs to the cadherin family of cell surface receptors and has been shown to play essential roles in the development of the vertebrate nervous system. Mutations in human Protocadherin-19 (PCDH19) lead to PCDH19 Female-limited epilepsy (PCDH19 FLE) in humans, characterized by the e...

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Bibliografiske detaljer
Udgivet i:Neuroscience
Main Authors: Emond, Michelle R., Biswas, Sayantanee, Morrow, Matthew L., Jontes, James D.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772771/
https://ncbi.nlm.nih.gov/pubmed/33010346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.09.033
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