Chicken optineurin suppresses MDA5-mediated interferon β production

Chicken MDA5 (chMDA5), the essential accepted pattern recognition receptors for detecting cytoplasmic viral RNA in chicken, initiates interferon β (IFN-β) generation. However, there is an incomplete elucidation of regulating chMDA5-mediated IFN-β production. NEMO-related protein, optineurin, was ide...

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Gepubliceerd in:Poult Sci
Hoofdauteurs: Li, Yu, Jiang, Ning, Mao, Yaqing, Zhang, Wenbo, Xiao, Jing, Wu, Xiangdong, Wu, Huansheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
Onderwerpen:
Immunology, Health and Disease
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772672/
https://ncbi.nlm.nih.gov/pubmed/33357711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psj.2020.08.020
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