Protocol to assess the efficacy of carnosine supplementation in mitigating the adverse cardiovascular responses to particulate matter (PM) exposure: the Nucleophilic Defense Against PM Toxicity (NEAT) trial

INTRODUCTION: Exposure to airborne particulate matter (PM) is associated with cardiovascular disease. These outcomes are believed to originate from pulmonary oxidative stress and the systemic delivery of oxidised biomolecules (eg, aldehydes) generated in the lungs. Carnosine is an endogenous di-pept...

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Dettagli Bibliografici
Pubblicato in:BMJ Open
Autori principali: O'Toole, Timothy E., Amraotkar, Alok A., DeFilippis, Andrew P., Rai, Shesh N., Keith, Rachel J., Baba, Shahid P., Lorkiewicz, Pawel, Crandell, Catherine E., Pariser, Gina L., Wingard, Christopher J., Pope III, C. Arden, Bhatnagar, Aruni
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2020
Soggetti:
Cardiovascular Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772308/
https://ncbi.nlm.nih.gov/pubmed/33372072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-039118
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