Brainstem and striatal volume changes are detectable in under 1 year and predict motor decline in spinocerebellar ataxia type 1

Spinocerebellar ataxia type 1 is a progressive neurodegenerative, movement disorder. With potential therapies on the horizon, it is critical to identify biomarkers that (i) differentiate between unaffected and spinocerebellar ataxia Type 1-affected individuals; (ii) track disease progression; and (i...

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Publicado en:Brain Commun
Autores principales: Koscik, Timothy R, Sloat, Lauren, van der Plas, Ellen, Joers, James M, Deelchand, Dinesh K, Lenglet, Christophe, Öz, Gülin, Nopoulos, Peggy C
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772094/
https://ncbi.nlm.nih.gov/pubmed/33409488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcaa184
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