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Origins, Development, Current Challenges and Future Directions with Activated Prothrombin Complex Concentrate for the Treatment of Patients with Congenital Haemophilia with Inhibitors
Congenital haemophilia A (HA) is caused by deficiency of coagulation factor VIII (FVIII) activity, leading to spontaneous or traumatic bleeding events. While FVIII replacement therapy can treat and prevent bleeds, approximately 30% of patients with severe HA develop inhibitor antibodies that render...
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| Udgivet i: | Hamostaseologie |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Georg Thieme Verlag KG
2020
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7772007/ https://ncbi.nlm.nih.gov/pubmed/32717751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-1159-4273 |
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