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Detecting Immune Response to Therapies Targeting PDL1 and BRAF by Using Ferumoxytol MRI and Macrin in Anaplastic Thyroid Cancer

BACKGROUND: Anaplastic thyroid cancer (ATC) is aggressive with a poor prognosis, partly because of the immunosuppressive microenvironment created by tumor-associated macrophages (TAMs). PURPOSE: To understand the relationship between TAM infiltration, tumor vascularization, and corresponding drug de...

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Опубликовано в: :Radiology
Главные авторы: Ng, Thomas S. C., Gunda, Viswanath, Li, Ran, Prytyskach, Mark, Iwamoto, Yoshiko, Kohler, Rainer H., Parangi, Sareh, Weissleder, Ralph, Miller, Miles A.
Формат: Artigo
Язык:Inglês
Опубликовано: Radiological Society of North America 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771993/
https://ncbi.nlm.nih.gov/pubmed/33107799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2020201791
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