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Prevalence of Germline Pathogenic and Likely Pathogenic Variants in Patients With Second Breast Cancers

BACKGROUND: Few studies have examined gene-specific associations with contralateral and/or second breast cancer (SBC). METHODS: The frequency of pathogenic and likely pathogenic (P/LP) variants in clinically actionable genes (BRCA1, BRCA2, PTEN, TP53, CHEK2, CDH1, ATM, PALB2, NBN, and NF1) was compa...

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Detalhes bibliográficos
Publicado no:JNCI Cancer Spectr
Main Authors: Yao K, Katharine A, Clifford, Jacob, Li, Shuwei, LaDuca, Holly, Hulick, Peter, Gutierrez, Stephanie, Black, Mary Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771422/
https://ncbi.nlm.nih.gov/pubmed/33409458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pkaa094
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