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An Aryl Hydrocarbon Receptor from the Caecilian Gymnopis multiplicata Suggests Low Dioxin Affinity in the Ancestor of All Three Amphibian Orders

The aryl hydrocarbon receptor (AHR) plays pleiotropic roles in the development and physiology of vertebrates in conjunction with xenobiotic and endogenous ligands. It is best known for mediating the toxic effects of dioxin-like pollutants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). While mos...

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Dettagli Bibliografici
Pubblicato in:Gen Comp Endocrinol
Autori principali: Kazzaz, Sarah A., Tagliabue, Sara Giani, Franks, Diana G., Denison, Michael S., Hahn, Mark E., Bonati, Laura, Powell, Wade H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771225/
https://ncbi.nlm.nih.gov/pubmed/32858041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygcen.2020.113592
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