Identification of novel substrates of a disintegrin and metalloprotease 17 by specific labeling of surface proteins

A disintegrin and metalloprotease 17 (ADAM17) catalyzes the cleavage and release of the ectodomains of its substrates at the cell surface in a process termed ectodomain shedding. However, not all ADAM17 substrates have been identified. Here, we used cell surface protein-specific labeling and proteom...

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Udgivet i:Heliyon
Main Authors: Omoteyama, Kazuki, Sato, Toshiyuki, Sato, Masaaki, Tsutiya, Atsuhiro, Arito, Mitsumi, Suematsu, Naoya, Kurokawa, Manae S., Kato, Tomohiro
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770542/
https://ncbi.nlm.nih.gov/pubmed/33385093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e05804
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