Three-dimensional spheroid culture of canine hepatocyte-like cells derived from bone marrow mesenchymal stem cells

INTRODUCTION: Primary cultured hepatocytes are an important model for early safety evaluations of newly developed drugs. Many factors, however, hinder the wider applications of this technology, especially the difficulty to maintain these cells in long-term culture. To date, creating a stable supply...

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Bibliografiske detaljer
Udgivet i:Regen Ther
Main Authors: Nitta, Suguru, Hisasue, Masaharu, Horiguchi, Yu, Yamada, Yoko, Kikuchi, Kaoruko, Kubo, Takeaki, Igarashi, Hirotaka, Neo, Sakurako
Format: Artigo
Sprog:Inglês
Udgivet: Japanese Society for Regenerative Medicine 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770424/
https://ncbi.nlm.nih.gov/pubmed/33426221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2020.09.002
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