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Three-dimensional spheroid culture of canine hepatocyte-like cells derived from bone marrow mesenchymal stem cells

INTRODUCTION: Primary cultured hepatocytes are an important model for early safety evaluations of newly developed drugs. Many factors, however, hinder the wider applications of this technology, especially the difficulty to maintain these cells in long-term culture. To date, creating a stable supply...

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Détails bibliographiques
Publié dans:Regen Ther
Auteurs principaux: Nitta, Suguru, Hisasue, Masaharu, Horiguchi, Yu, Yamada, Yoko, Kikuchi, Kaoruko, Kubo, Takeaki, Igarashi, Hirotaka, Neo, Sakurako
Format: Artigo
Langue:Inglês
Publié: Japanese Society for Regenerative Medicine 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770424/
https://ncbi.nlm.nih.gov/pubmed/33426221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2020.09.002
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