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Recombinant canine basic fibroblast growth factor-induced differentiation of canine bone marrow mesenchymal stem cells into voltage- and glutamate-responsive neuron-like cells

INTRODUCTION: Basic fibroblast growth factor (bFGF) is a promising cytokine in regenerative therapy for spinal cord injury. In this study, recombinant canine bFGF (rc-bFGF) was synthesized for clinical use in dogs, and the ability of rc-bFGF to differentiate canine bone marrow mesenchymal stem cells...

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Détails bibliographiques
Publié dans:Regen Ther
Auteurs principaux: Edamura, Kazuya, Takahashi, Yusuke, Fujii, Airi, Masuhiro, Yoshikazu, Narita, Takanori, Seki, Mamiko, Asano, Kazushi
Format: Artigo
Langue:Inglês
Publié: Japanese Society for Regenerative Medicine 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770349/
https://ncbi.nlm.nih.gov/pubmed/33426210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2020.07.005
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