The Roles of High Mobility Group Box 1 in Cerebral Ischemic Injury

High mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that plays an important role in stabilizing nucleosomes and DNA repair. HMGB1 can be passively released from necrotic neurons or actively secreted by microglia, macrophages/monocytes, and neutrophils. Cerebral ischemia is a major caus...

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Pubblicato in:Front Cell Neurosci
Autori principali: Gou, Xiaoyun, Ying, Junjie, Yue, Yan, Qiu, Xia, Hu, Peng, Qu, Yi, Li, Jinhui, Mu, Dezhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cellular Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770223/
https://ncbi.nlm.nih.gov/pubmed/33384585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.600280
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