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Guide RNA categorization enables target site choice in Tn7-CRISPR-Cas transposons
CRISPR-Cas defense systems have been coopted multiple times in nature for guide RNA-directed transposition by Tn7-like elements. Prototypic Tn7 uses dedicated proteins for two targeting pathways, one targeting a neutral and conserved attachment site in the chromosome and a second directing transposi...
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| Pubblicato in: | Cell |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7770071/ https://ncbi.nlm.nih.gov/pubmed/33271061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.11.005 |
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