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Design of a Randomized Clinical Trial of Perioperative Vaginal Estrogen Versus Placebo with Transvaginal Native Tissue Apical Prolapse Repair (Investigation to Minimize Prolapse Recurrence Of the Vagina using Estrogen: IMPROVE)

OBJECTIVES: To provide the rationale and design for a randomized, double-blind clinical trial of conjugated estrogen vaginal cream (applied for at least 5 weeks preoperatively and continued twice-weekly through 12 months postoperatively) compared with placebo in postmenopausal women with symptomatic...

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Detalhes bibliográficos
Publicado no:Female Pelvic Med Reconstr Surg
Main Authors: Rahn, David D., Richter, Holly E., Sung, Vivian W., Larsen, Wilma I., Hynan, Linda S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769931/
https://ncbi.nlm.nih.gov/pubmed/32541299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SPV.0000000000000899
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