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Clopidogrel responder status is uninfluenced by CYP2C19*2 in Danish patients with stroke

BACKGROUND: Antiplatelet therapy is a cornerstone of secondary stroke prevention, but the responsiveness to antiplatelet medication varies among patients. Clopidogrel is a pro-drug that requires hepatic transformation to reach its active metabolite. Single nucleotide polymorphisms (SNPs) in key enzy...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rath, Charlotte Lützhøft, Jørgensen, Niklas Rye, Wienecke, Troels
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769274/
https://ncbi.nlm.nih.gov/pubmed/33370281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236260
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