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Belimumab Alters Transitional B Cell Subset Proportions in Stable Systemic Lupus Erythematosus Patients

OBJECTIVE: We evaluated the effects of the BAFF targeting antibody, Belimumab, on human nonmemory B cell pools. Human B cell pools were identified using surface markers adapted from mouse studies that specifically assessed reductions in immature B cells due to BAFF-depletion. SLE patients have high...

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Dettagli Bibliografici
Pubblicato in:Lupus
Autori principali: Benitez, Abigail, Torralba, Karina, Ngo, Michelle, Salto, Lorena M., Choi, Kristal S., De Vera, Michael E., Payne, Kimberly J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769209/
https://ncbi.nlm.nih.gov/pubmed/31423896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203319869468
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