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Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins

As intracellular parasites, viruses hijack the host cell metabolic machinery for their replication. Among other cellular proteins, the DEAD-box (DDX) RNA helicases have been shown to be hijacked by coronaviruses and to participate in essential DDX-mediated viral replication steps. Human DDX RNA heli...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Squeglia, Flavia, Romano, Maria, Ruggiero, Alessia, Maga, Giovanni, Berisio, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769135/
https://ncbi.nlm.nih.gov/pubmed/33381492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.602162
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