Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine

We previously reported that topical imiquimod can improve the immunogenicity of the influenza vaccine. This study investigated another FDA-approved drug, miltefosine (MTF), as a vaccine adjuvant. Mice immunized with an influenza vaccine with or without MTF adjuvant were challenged by a lethal dose o...

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Vydáno v:Vaccines (Basel)
Hlavní autoři: Lu, Lu, Fong, Carol Ho-Yan, Zhang, Anna Jinxia, Wu, Wai-Lan, Li, Iris Can, Lee, Andrew Chak-Yiu, Dissanayake, Thrimendra Kaushika, Chen, Linlei, Hung, Ivan Fan-Ngai, Chan, Kwok-Hung, Chu, Hin, Kok, Kin-Hang, Yuen, Kwok-Yung, To, Kelvin Kai-Wang
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768360/
https://ncbi.nlm.nih.gov/pubmed/33322574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040754
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