Oxidative DNA Damage, Inflammatory Signature, and Altered Erythrocytes Properties in Diamond-Blackfan Anemia

Molecular pathophysiology of Diamond-Blackfan anemia (DBA) involves disrupted erythroid-lineage proliferation, differentiation and apoptosis; with the activation of p53 considered as a key component. Recently, oxidative stress was proposed to play an important role in DBA pathophysiology as well. CR...

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Publicat a:Int J Mol Sci
Autors principals: Kapralova, Katarina, Jahoda, Ondrej, Koralkova, Pavla, Gursky, Jan, Lanikova, Lucie, Pospisilova, Dagmar, Divoky, Vladimir, Horvathova, Monika
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768356/
https://ncbi.nlm.nih.gov/pubmed/33348919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249652
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