Mechanical Feed-Forward Loops Contribute to Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis is a progressive scarring disease characterized by extracellular matrix accumulation and altered mechanical properties of lung tissue. Recent studies support the hypothesis that these compositional and mechanical changes create a progressive feed-forward loop in which e...

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Bibliographic Details
Published in:Am J Pathol
Main Authors: Freeberg, Margaret A.T., Perelas, Apostolos, Rebman, Jane K., Phipps, Richard P., Thatcher, Thomas H., Sime, Patricia J.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768346/
https://ncbi.nlm.nih.gov/pubmed/33031756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.09.008
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