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Co-evolution of mutagenic genome editors and vertebrate adaptive immunity
The adaptive immune systems of all vertebrates rely on self-DNA mutating enzymes to assemble their antigen receptors in lymphocytes of their two principal lineages. In jawed vertebrates, the RAG1/2 recombinase directs V(D)J recombination of B cell and T cell receptor genes, whereas the activation-in...
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| Publicado no: | Curr Opin Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7768089/ https://ncbi.nlm.nih.gov/pubmed/32353821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2020.03.001 |
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