The Reducing Effects of Pyrogallol-Phloroglucinol-6,6-Bieckol on High-Fat Diet-Induced Pyroptosis in Endothelial and Vascular Smooth Muscle Cells of Mice Aortas

In hyperlipidemia, pyroptosis in endothelial cells (ECs) induces atherosclerosis via the toll-like receptor 4 (TLR4) pathway. We evaluated the effects of Ecklonia cava extract (ECE) and pyrogallol-phloroglucinol-6,6-bieckol (PPB) on pyroptosis of ECs and vascular smooth muscle cells (VSMCs), which l...

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Publicado en:Mar Drugs
Main Authors: Oh, Seyeon, Son, Myeongjoo, Park, Chul-Hyun, Jang, Ji Tae, Son, Kuk Hui, Byun, Kyunghee
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766911/
https://ncbi.nlm.nih.gov/pubmed/33339328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18120648
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