Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study

Nanomedicines are a novel class of therapeutics that benefit from the nano dimensions of the drug carrier. These nanosystems are highly advantageous mainly within cancer treatment due to their enhanced tumor accumulation. Monolayer tumor cells frequently used in routine preclinical assessment of nan...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Kudláčová, Júlia, Kotrchová, Lenka, Kostka, Libor, Randárová, Eva, Filipová, Marcela, Janoušková, Olga, Fang, Jun, Etrych, Tomáš
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766879/
https://ncbi.nlm.nih.gov/pubmed/33419291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121242
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