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Implication of the Association of Fibrinogen Citrullination and Osteoclastogenesis in Bone Destruction in Rheumatoid Arthritis

Immune complexes containing citrullinated fibrinogen are present in the sera and synovium of rheumatoid arthritis patients and potentially contribute to synovitis. However, fibrinogen can inhibit the osteoclastogenesis of precursor cells. We investigated the direct effect of citrullinated fibrinogen...

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Publicado en:Cells
Autores principales: Kim, Ji Soo, Choi, Mikyung, Choi, Ji Yong, Kim, Joo Yeon, Kim, Jeong Yeon, Song, Jin-Su, Ivashkiv, Lionel B., Lee, Eun Young
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766778/
https://ncbi.nlm.nih.gov/pubmed/33419308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122720
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