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Macrocybin, a Natural Mushroom Triglyceride, Reduces Tumor Growth In Vitro and In Vivo through Caveolin-Mediated Interference with the Actin Cytoskeleton

Mushrooms have been used for millennia as cancer remedies. Our goal was to screen several mushroom species from the rainforests of Costa Rica, looking for new antitumor molecules. Mushroom extracts were screened using two human cell lines: A549 (lung adenocarcinoma) and NL20 (immortalized normal lun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Vilariño, Marcos, García-Sanmartín, Josune, Ochoa-Callejero, Laura, López-Rodríguez, Alberto, Blanco-Urgoiti, Jaime, Martínez, Alfredo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766322/
https://ncbi.nlm.nih.gov/pubmed/33353176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25246010
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