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A Reliable Enantioselective Route to Mono-Protected N1-Cbz Piperazic Acid Building Block

The chiral N1-Cbz, N2-H derivative of the piperazic acid monomer is a valuable building block in the total synthesis of natural products, comprising this nonproteinogenic amino acid. In that context, we wish to report an improved synthetic protocol for the synthesis of both (3R)- and (3S)-piperazic...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Papadaki, Evanthia, Georgiadis, Dimitris, Tsakos, Michail
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765410/
https://ncbi.nlm.nih.gov/pubmed/33333919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25245939
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