Epigenetic Silencing of Tumor Suppressor miR-124 Directly Supports STAT3 Activation in Cutaneous T-Cell Lymphoma

Increasing evidence supports a potential role for STAT3 as a tumor driver in cutaneous T-cell lymphomas (CTCL). The mechanisms leading to STAT3 activation are not fully understood; however, we recently found that miR-124, a known STAT3 regulator, is robustly silenced in MF tumor-stage and CTCL cells...

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Main Authors: García-Colmenero, Lidia, González, Jéssica, Sandoval, Juan, Guillén, Yolanda, Diaz-Lagares, Angel, Andrades, Evelyn, Iglesias, Arnau, Nonell, Lara, Pujol, Ramon Maria, Bigas, Anna, Espinosa, Lluís, Gallardo, Fernando
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765332/
https://ncbi.nlm.nih.gov/pubmed/33333886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122692
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