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Molecular Mechanisms That Link Oxidative Stress, Inflammation, and Fibrosis in the Liver
Activated hepatic stellate cells (HSCs) and myofibroblasts are the main producers of extracellular matrix (ECM) proteins that form the fibrotic tissue that leads to hepatic fibrosis. Reactive oxygen species (ROS) can directly activate HSCs or induce inflammation or programmed cell death, especially...
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| Published in: | Antioxidants (Basel) |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7765317/ https://ncbi.nlm.nih.gov/pubmed/33333846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121279 |
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