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Comprehensive Mutational and Phenotypic Characterization of New Metastatic Cutaneous Squamous Cell Carcinoma Cell Lines Reveal Novel Drug Susceptibilities

Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer. Most patients who develop metastases (2–5%) present with advanced disease that requires a combination of radical surgery and adjuvant radiation therapy. There are few effective therapies for refractory disease. In this study, we descr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Perry, Jay, Ashford, Bruce, Thind, Amarinder Singh, Gauthier, Marie-Emilie, Minaei, Elahe, Major, Gretel, Iyer, Narayanan Gopalakrishna, Gupta, Ruta, Clark, Jonathan, Ranson, Marie
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765308/
https://ncbi.nlm.nih.gov/pubmed/33333825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249536
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