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The PARP Inhibitor Olaparib Modulates the Transcriptional Regulatory Networks of Long Non-Coding RNAs during Vasculogenic Mimicry

In highly metastatic tumors, vasculogenic mimicry (VM) involves the acquisition by tumor cells of endothelial-like traits. Poly-(ADP-ribose) polymerase (PARP) inhibitors are currently used against tumors displaying BRCA1/2-dependent deficient homologous recombination, and they may have antimetastati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Fernández-Cortés, Mónica, Andrés-León, Eduardo, Oliver, Francisco Javier
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765283/
https://ncbi.nlm.nih.gov/pubmed/33333852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122690
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