Role and Regulation of Mechanotransductive HIF-1α Stabilisation in Periodontal Ligament Fibroblasts

Orthodontic tooth movement (OTM) creates compressive and tensile strain in the periodontal ligament, causing circulation disorders. Hypoxia-inducible factor 1α (HIF-1α) has been shown to be primarily stabilised by compression, but not hypoxia in periodontal ligament fibroblasts (PDLF) during mechani...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kirschneck, Christian, Thuy, Magdalena, Leikam, Alexandra, Memmert, Svenja, Deschner, James, Damanaki, Anna, Spanier, Gerrit, Proff, Peter, Jantsch, Jonathan, Schröder, Agnes
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765204/
https://ncbi.nlm.nih.gov/pubmed/33333756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249530
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