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N-Heterocycles Scaffolds as Quorum Sensing Inhibitors. Design, Synthesis, Biological and Docking Studies

Quorum sensing is a communication system among bacteria to sense the proper time to express their virulence factors. Quorum sensing inhibition is a therapeutic strategy to block bacterial mechanisms of virulence. The aim of this study was to synthesize and evaluate new bioisosteres of N-acyl homoser...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Fuentes-Gutiérrez, Alfredo, Curiel-Quesada, Everardo, Correa-Basurto, José, Martínez-Muñoz, Alberto, Reyes-Arellano, Alicia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765044/
https://ncbi.nlm.nih.gov/pubmed/33327584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249512
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