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Stem Cell-Derived Exosomes Ameliorate Doxorubicin-Induced Muscle Toxicity through Counteracting Pyroptosis

Doxorubicin (Dox)-induced muscle toxicity (DIMT) is a common occurrence in cancer patients; however, the cause of its development and progression is not established. We tested whether inflammation-triggered cell death, “pyroptosis” plays a role in DIMT. We also examined the potential role of exosome...

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Bibliografiske detaljer
Udgivet i:Pharmaceuticals (Basel)
Main Authors: Dessouki, Fatima Bianca A., Kukreja, Rakesh C., Singla, Dinender K.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764639/
https://ncbi.nlm.nih.gov/pubmed/33316945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13120450
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