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Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis

SIMPLE SUMMARY: In vitro models able to represent osteoarthritis (OA) synovial tissue (ST) inflammation are lacking. Therefore, we aimed to characterize OA ST and to compare mechanical and enzymatic digestion procedures to find the one that better preserve the heterogeneity of the main OA synovial c...

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Dettagli Bibliografici
Pubblicato in:Biology (Basel)
Autori principali: Manferdini, Cristina, Saleh, Yasmin, Dolzani, Paolo, Gabusi, Elena, Trucco, Diego, Filardo, Giuseppe, Lisignoli, Gina
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764613/
https://ncbi.nlm.nih.gov/pubmed/33321965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9120459
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