Comprehensive Analysis of SWI/SNF Inactivation in Lung Adenocarcinoma Cell Models

SIMPLE SUMMARY: Mammalian SWI/SNF complexes regulate gene expression by reorganizing the way DNA is packaged into chromatin. SWI/SNF subunits are recurrently altered in tumors at multiple levels, including DNA mutations as well as alteration of the levels of RNA and protein. Cancer cell lines are of...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Peinado, Paola, Andrades, Alvaro, Cuadros, Marta, Rodriguez, Maria Isabel, Coira, Isabel F., Garcia, Daniel J., Álvarez-Perez, Juan Carlos, Baliñas-Gavira, Carlos, Arenas, Alberto M., Patiño-Mercau, Juan Rodrigo, Sanjuan-Hidalgo, Juan, Romero, Octavio A., Montuenga, Luis M., Carretero, Julian, Sanchez-Cespedes, Montserrat, Medina, Pedro P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763689/
https://ncbi.nlm.nih.gov/pubmed/33321963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123712
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