Dissolution Enhancement and Controlled Release of Paclitaxel Drug via a Hybrid Nanocarrier Based on mPEG-PCL Amphiphilic Copolymer and Fe-BTC Porous Metal-Organic Framework

In the present work, the porous metal-organic framework (MOF) Basolite(®)F300 (Fe-BTC) was tested as a potential drug-releasing depot to enhance the solubility of the anticancer drug paclitaxel (PTX) and to prepare controlled release formulations after its encapsulation in amphiphilic methoxy poly(e...

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Publicat a:Nanomaterials (Basel)
Autors principals: Bikiaris, Nikolaos D., Ainali, Nina Maria, Christodoulou, Evi, Kostoglou, Margaritis, Kehagias, Thomas, Papasouli, Emilia, Koukaras, Emmanuel N., Nanaki, Stavroula G.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763675/
https://ncbi.nlm.nih.gov/pubmed/33322372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano10122490
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