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Towards Deep Neural Network Models for the Prediction of the Blood–Brain Barrier Permeability for Diverse Organic Compounds

Permeation through the blood–brain barrier (BBB) is among the most important processes controlling the pharmacokinetic properties of drugs and other bioactive compounds. Using the fragmental (substructural) descriptors representing the occurrence number of various substructures, as well as the artif...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Radchenko, Eugene V., Dyabina, Alina S., Palyulin, Vladimir A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763607/
https://ncbi.nlm.nih.gov/pubmed/33322142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25245901
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