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The Two-Component System CopRS Maintains Subfemtomolar Levels of Free Copper in the Periplasm of Pseudomonas aeruginosa Using a Phosphatase-Based Mechanism
Two-component systems control periplasmic Cu(+) homeostasis in Gram-negative bacteria. In characterized systems such as Escherichia coli CusRS, upon Cu(+) binding to the periplasmic sensing region of CusS, a cytoplasmic phosphotransfer domain of the sensor phosphorylates the response regulator CusR....
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| Publicado no: | mSphere |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7763554/ https://ncbi.nlm.nih.gov/pubmed/33361129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.01193-20 |
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