Analysis of Serial Multidrug-Resistant Tuberculosis Strains Causing Treatment Failure and Within-Host Evolution by Whole-Genome Sequencing

The cure rate of multidrug-resistant tuberculosis (MDR-TB) is relatively low in China. The reasons for the treatment failure and within-host evolution during treatment have not been sufficiently studied. All MDR-TB patients receiving standard treatment from January 2014 to September 2016 at a design...

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Veröffentlicht in:mSphere
Hauptverfasser: Chen, Xinchang, He, Guiqing, Lin, Siran, Wang, Shiyong, Sun, Feng, Chen, Jiazhen, Zhang, Wenhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763549/
https://ncbi.nlm.nih.gov/pubmed/33361124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00884-20
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