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Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL

Hdac3 is a lysine deacetylase that removes acetyl groups from histones and additional proteins. Although Hdac3 functions within mesenchymal lineage skeletal cells are defined, little is known about Hdac3 activities in bone-resorbing osteoclasts. In this study we conditionally deleted Hdac3 within Ct...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Molstad, David H. H., Mattson, Anna M., Begun, Dana L., Westendorf, Jennifer J., Bradley, Elizabeth W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762944/
https://ncbi.nlm.nih.gov/pubmed/33454009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013573
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